ProteinHistorian identifies enrichment for proteins of different phylogenetic ages in protein sets of interest. ProteinHistorian is to evolutionary history as Gene Ontology term enrichment analysis is to function. Over thirty eukaryotic species are currently supported. Other protein attributes can be uploaded to combine with the protein age analysis. ProteinHistorian is described in the following paper:
Please cite the paper if you use any of the resources below.
Capra JA, Williams AG, and Pollard KS. ProteinHistorian: Tools for the Comparative Analysis of Eukaryote Protein Origin. PLoS Computational Biology, In Press, 2012.
Age data for proteins in all species and open source command line versions of the protein age enrichment analysis scripts are available on the downloads page. Details of the creation and contents of the databases are available on the methods page. Frequently asked questions are answered in the FAQ.
Run ProteinHistorian with your own data:(Or use the example data that is already in place.)
Age data for proteins in all species and open source command line versions of the protein age enrichment analysis scripts are available.
This page provides details on the creation and contents of the databases available for each species.
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