ProteinHistorian Methods

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ProteinHistorian provides pre-computed ages based on several external databses of protein families and two algorithms for ancestral family reconstruction. The "age" of a protein can differ considerably depending on the database and algorithm used. This page provides descriptions and links to more information about the databases and algorithms used by ProteinHistorian. For more information, read the paper and see the FAQ. Please cite the appropriate references, in addition to the ProteinHistorian paper, if you use results based on any of these databses.

For most phylogenetic databases, the TimeTree database was used to translate phylogenetic ages based on a species tree to age estimates in millions of years ago.

Protein Family Databases

Ancestral Reconstruction Algorithms

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